Service Dog Project, Inc. has trained and donated over 45 Great Danes to people who are mobility- impaired, according to their webpage.
focus "...is training Great Danes and other large breed dogs to assist
balance-impaired people. This would include, but not be restricted to,
Parkinson’s and MS patients. Preference is given to Veterans and their
The kennels, located on 12 acres in Ipswich, Massachusetts, include outdoor and indoor training areas
on the farm, and provide the necessary space to raise these dogs from birth
to graduation to retirement.